Abstract
ptical coherence tomography (OCT) is now state of the art in ophthalmology. Other medical departments, such as otolaryngology, could also benefit from this imaging modality. Polarization is a property which is a benefit to conventional OCT. It can be used in particular to detect birefringent tissue layers. To evaluate possible OCT applications in Ear, Nose and Throat (ENT) department, a fiber-based polarization-sensitive OCT (PS- OCT) is used to measure human ex-vivo tissue biopsies. A total of 58 samples from 20 different tissues were measured.
The measurements show that small biopsies lose their birefrin- gent property, this leads to the assumption that tissue-matrices lose tension and molecular order. Larger samples show phase retardation and are used to detect different birefringent layers of tissue. We also show a method of verifying cancer diagnosis by displaying the tissue layer structure.
As a conclusion, PS-OCT may improve cancer diagnosis in ENT.
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@conference{Fleischhauer2013,
title = {Polarization-sensitive optical coherence tomography on different tissues samples for tumor discrimination},
author = {Felix Fleischhauer and Hinnerk Schulz-Hildebrandt and Tim Bonin and Gereon H\"{u}ttmann },
url = {http://www.bmo.uni-luebeck.de/fileadmin/files/publications/Fleischhauer__2013_Polarization-sensitive_optical_coherence_tomography.pdf},
year = {2013},
date = {2013-07-01},
booktitle = {Student Conference Medical Engineering Science 2013: Proceedings},
volume = {2},
pages = {38},
publisher = {GRIN Verlag},
abstract = {ptical coherence tomography (OCT) is now state of the art in ophthalmology. Other medical departments, such as otolaryngology, could also benefit from this imaging modality. Polarization is a property which is a benefit to conventional OCT. It can be used in particular to detect birefringent tissue layers. To evaluate possible OCT applications in Ear, Nose and Throat (ENT) department, a fiber-based polarization-sensitive OCT (PS- OCT) is used to measure human ex-vivo tissue biopsies. A total of 58 samples from 20 different tissues were measured.
The measurements show that small biopsies lose their birefrin- gent property, this leads to the assumption that tissue-matrices lose tension and molecular order. Larger samples show phase retardation and are used to detect different birefringent layers of tissue. We also show a method of verifying cancer diagnosis by displaying the tissue layer structure.
As a conclusion, PS-OCT may improve cancer diagnosis in ENT.},
keywords = {OCT, Optical coherence tomography, PS-OCT},
pubstate = {published},
tppubtype = {conference}
}