Mario Pieper; Hinnerk Schulz-Hildebrandt; Marcus A Mall; Gereon Hüttmann; Peter König Intravital microscopy of mucus transport in mice provides mechanistic insight into hypertonic saline treatment of Cystic Fibrosis Conference Pneumologie, vol. 70, 2016. @conference{Pieper2016,
title = {Intravital microscopy of mucus transport in mice provides mechanistic insight into hypertonic saline treatment of Cystic Fibrosis},
author = {Mario Pieper and Hinnerk Schulz-Hildebrandt and Marcus A Mall and Gereon H\"{u}ttmann and Peter K\"{o}nig},
editor = {Thieme},
doi = {10.1055/s-0036-1584654},
year = {2016},
date = {2016-07-01},
booktitle = {Pneumologie},
volume = {70},
pages = {SOP2},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
|
Ellen Guder; Eva Lankenau; Felix Fleischhauer; Hinnerk Schulz-Hildebrandt; Gereon Hüttmann; HW Pau; Tino Just Microanatomy of the tympanic membrane in chronic myringitis obtained with optical coherence tomography Journal Article In: European Archives of Oto-Rhino-Laryngology, vol. 272, no. 11, pp. 3217-3223, 2015, ISSN: 1434-4726. @article{Guder2015,
title = {Microanatomy of the tympanic membrane in chronic myringitis obtained with optical coherence tomography},
author = {Ellen Guder and Eva Lankenau and Felix Fleischhauer and Hinnerk Schulz-Hildebrandt and Gereon H\"{u}ttmann and HW Pau and Tino Just},
editor = {Springer Berlin Heidelberg},
url = {https://link.springer.com/article/10.1007/s00405-014-3373-z},
doi = {doi.org/10.1007/s00405-014-3373-z},
issn = {1434-4726},
year = {2015},
date = {2015-11-11},
journal = {European Archives of Oto-Rhino-Laryngology},
volume = {272},
number = {11},
pages = {3217-3223},
abstract = {© 2014, Springer-Verlag Berlin Heidelberg. A microscope-based optical coherence tomography (OCT) device was used to assess the microanatomy of the tympanic membrane in patients with chronic myringitis. A prospective study was designed for this purpose. OCT measurements of the tympanic membrane were done on 11 patients with myringitis with a microscope-based spectral domain OCT system. The in vivo findings were compared with those findings of a control group consisting of 36 patients with retraction pockets or atrophic tympanic membranes (n = 13), myringosclerosis (n = 12) and perforations (n = 11). In active chronic myringitis, the thickness of the tympanic membrane is increased compared to healthy membranes and to other pathological conditions of the tympanic membrane. Consistent changes of the microanatomy of the tympanic membrane were found in chronic myringitis with OCT. Serial OCT measurements revealed no biofilm suspicious findings in all patients with active chronic myringitis. Intraoperative and in vivo OCT measurements may help to detect microanatomical changes of the tympanic membrane in chronic myringitis and in other conditions of the tympanic membrane.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
© 2014, Springer-Verlag Berlin Heidelberg. A microscope-based optical coherence tomography (OCT) device was used to assess the microanatomy of the tympanic membrane in patients with chronic myringitis. A prospective study was designed for this purpose. OCT measurements of the tympanic membrane were done on 11 patients with myringitis with a microscope-based spectral domain OCT system. The in vivo findings were compared with those findings of a control group consisting of 36 patients with retraction pockets or atrophic tympanic membranes (n = 13), myringosclerosis (n = 12) and perforations (n = 11). In active chronic myringitis, the thickness of the tympanic membrane is increased compared to healthy membranes and to other pathological conditions of the tympanic membrane. Consistent changes of the microanatomy of the tympanic membrane were found in chronic myringitis with OCT. Serial OCT measurements revealed no biofilm suspicious findings in all patients with active chronic myringitis. Intraoperative and in vivo OCT measurements may help to detect microanatomical changes of the tympanic membrane in chronic myringitis and in other conditions of the tympanic membrane. |
Felix Fleischhauer; Hinnerk Schulz-Hildebrandt; Tim Bonin; Gereon Hüttmann Polarization-sensitive optical coherence tomography on different tissues samples for tumor discrimination Conference Student Conference Medical Engineering Science 2013: Proceedings, vol. 2, GRIN Verlag, 2013. @conference{Fleischhauer2013,
title = {Polarization-sensitive optical coherence tomography on different tissues samples for tumor discrimination},
author = {Felix Fleischhauer and Hinnerk Schulz-Hildebrandt and Tim Bonin and Gereon H\"{u}ttmann },
url = {http://www.bmo.uni-luebeck.de/fileadmin/files/publications/Fleischhauer__2013_Polarization-sensitive_optical_coherence_tomography.pdf},
year = {2013},
date = {2013-07-01},
booktitle = {Student Conference Medical Engineering Science 2013: Proceedings},
volume = {2},
pages = {38},
publisher = {GRIN Verlag},
abstract = {ptical coherence tomography (OCT) is now state of the art in ophthalmology. Other medical departments, such as otolaryngology, could also benefit from this imaging modality. Polarization is a property which is a benefit to conventional OCT. It can be used in particular to detect birefringent tissue layers. To evaluate possible OCT applications in Ear, Nose and Throat (ENT) department, a fiber-based polarization-sensitive OCT (PS- OCT) is used to measure human ex-vivo tissue biopsies. A total of 58 samples from 20 different tissues were measured.
The measurements show that small biopsies lose their birefrin- gent property, this leads to the assumption that tissue-matrices lose tension and molecular order. Larger samples show phase retardation and are used to detect different birefringent layers of tissue. We also show a method of verifying cancer diagnosis by displaying the tissue layer structure.
As a conclusion, PS-OCT may improve cancer diagnosis in ENT.},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
ptical coherence tomography (OCT) is now state of the art in ophthalmology. Other medical departments, such as otolaryngology, could also benefit from this imaging modality. Polarization is a property which is a benefit to conventional OCT. It can be used in particular to detect birefringent tissue layers. To evaluate possible OCT applications in Ear, Nose and Throat (ENT) department, a fiber-based polarization-sensitive OCT (PS- OCT) is used to measure human ex-vivo tissue biopsies. A total of 58 samples from 20 different tissues were measured.
The measurements show that small biopsies lose their birefrin- gent property, this leads to the assumption that tissue-matrices lose tension and molecular order. Larger samples show phase retardation and are used to detect different birefringent layers of tissue. We also show a method of verifying cancer diagnosis by displaying the tissue layer structure.
As a conclusion, PS-OCT may improve cancer diagnosis in ENT. |